Mechanism of action:
This drug work by binding to calcium channels found on nerve cells in the brain and spinal cord. This reduces the release of various neurotransmitters from these nerve cells.Neurotransmitters are natural body chemicals that are stored in nerve cells. They are involved in transmitting messages between the nerve cells. Pregabalin is thought to reduce the release of neurotransmitters called glutamate, noradrenaline and substance P.
Glutamate is a neurotransmitter that acts as a natural 'nerve-exciting' agent. It is released when electrical signals build up in nerve cells and subsequently excites more nerve cells. It is thought to play a key role in causing epileptic seizures. Reducing the release of glutamate from the nerve cells in the brain is thought to help stabilize the electrical activity in the brain and prevent epileptic fits.
What is it used for?
- Epilepsy - used as an add-on therapy for adults with partial seizures with or without secondary generalization.
- Nerve pain (peripheral and central neuropathic pain) in adults, for example due to diabetic neuropathy, following shingles (post-herpetic neuralgia) or due to spinal cord injury.
- Generalized anxiety disorder in adults.
- This capsule can be taken either with or without food.
- These drugs are usually taken two to three times a day. The dose prescribed depends on the individual Wholesale Canucks Jerseys , the condition being treated and how well it is controlled.
- If you have epilepsy it is important to take your medication regularly, as directed by your doctor, because missing doses can trigger seizures in some people. If you have trouble remembering to take your medicine you should ask your pharmacist for advice. You may find a pill reminder box helpful.
- You should not stop taking this medicine suddenly unless your doctor tells you otherwise, as this may result in your seizures Cheap Vancouver Canucks Jerseys , nerve pain or anxiety returning or getting worse. If it is decided that you should stop taking this medicine, the dose should usually be reduced gradually over at least a week. Follow the instructions given by your doctor.
- This medicine may cause dizziness, sleepiness, confusion or blurred vision and so may reduce your ability to drive or operate machinery safely. Do not drive or operate machinery until you know how this medicine affects you and you are sure it won't affect your performance.
- This medicine may increase the effects of alcohol.
- There may be a small increased risk of suicidal thoughts and behavior in people taking antiepileptic medicines such as pregabalin for any condition. For this reason Cheap Canucks Jerseys , it is very important to seek medical advice if you or someone else taking this medicine, experience any changes in mood, distressing thoughts, or feelings about suicide or self-harm at any point while taking this medicine.
- This medicine may cause skin reactions. You should let your doctor know if you develop a rash Wholesale Sam Gagner Jersey , skin peeling, itching, or other unexplained skin reaction while taking this medicine.
- This medicine may sometimes cause allergic reactions, including angioedema. Consult your doctor immediately if you experience difficulty breathing or swallowing Wholesale Jay Beagle Jersey , or swelling of your face, lips, tongue or throat while taking this medicine.
- Some people have experienced withdrawal symptoms after stopping treatment (long-term or short-term) with this medicine. These have included insomnia, headache Wholesale Markus Granlund Jersey , nausea, diarrhea, flu syndrome, nervousness Wholesale Tim Schaller Jersey , depression, pain, sweating and dizziness.
Storage:
Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).
Foreign currency trading is a high risk and high reward business. You need to devise strategies to make profits in the market on a sustained basis. Always remember that day trading in foreign currency is not the ideal way if you really want to have a long term perspective.
Day trading in foreign currency exchange is the same concept as day trading in securities markets. You take a short term bet on the price movements of various currencies in your portfolio. Thus you gain or lose depending upon the intra day fluctuations in prices of these currencies. Whether you are long or short at a particular point of time in a day depends upon your assessment of the likelihood movement of prices later on during the day. Let us explain by a simple example. Suppose you are short on Yen in the morning session of trading (meaning that you have sold yen at a price). It means that you expect Yen to decline further in the day so that you would be able to buy back Yen at a lower price and make a profit in the proc. Cheap Jerseys China Cheap Jerseys China Cheap Jerseys China Wholesale Cheap Jerseys Online Cheap Jerseys China Wholesale Cheap NHL Jerseys China Cheap NFL Jerseys China Cheap Nike NFL Jerseys Wholesale Cheap College Jerseys Wholesale Cheap Nike NBA Jerseys Free Shipping
Precaution:
Dosage:
