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CHICAGO [url=http://www.cheapjerseystexans.com/deshaun-watson-jersey/]Deshaun Watson Jersey[/url] , Nov. 7 (Xinhua) -- A previously dismissed genetic mechanism may contribute to nicotine dependence, and to the withdrawal effects that can make quitting smoking difficult, researchers at the University of Michigan (UM) Life Sciences Institute found.

UM researcher examined withdrawal responses in the millimeter-long roundworms Caenorhabditis elegans, which get hooked on nicotine just like humans, and discovered that a series of genes were involved in a process that ultimately increased the production of the nicotine receptor proteins [url=http://www.cheapjerseystexans.com/whitney-mercilus-jersey/]Whitney Mercilus Jersey[/url] , with microRNAs, a class of small RNA molecules that help fine-tune gene expression, playing a pivotal role.

"We're seeing a clear link between nicotine, microRNA, the receptor proteins [url=http://www.cheapjerseystexans.com/johnathan-joseph-jersey/]Johnathan Joseph Jersey[/url] , and nicotine-dependent behavior," said Jianke Gong, one of the lead authors on the study.

The findings have provided clues that may carry over to the mammalian realm, and may lead other scientists to re-examine the role of these microRNAs in nicotine dependence in mammals.

"We have better tools now. We, as a field [url=http://www.cheapjerseystexans.com/jadeveon-clowney-jersey/]Jadeveon Clowney Jersey[/url] , need to take another look at this mechanism in nicotine addiction," said Shawn Xu, professor of the Department of Molecular and Integrative Physiology at the UM Medical School.

The findings have been published in Cell Reports.

ISLAMABAD, June 1 (Xinhua) -- Pakistan on Thursday summoned Indian Deputy High Commissioner J.P. Singh and condemned the "unprovoked ceasefire violations by the Indian forces" that killed at least two civilians and injured five others in the disputed Kashmir region.

The Pakistan army said Indian forces initiated unprovoked firing at Batal, Jandrot and Hotspring sectors along the Line of Control (LoC) in Kashmir on Thursday morning.

The Foreign Ministry said the Indian firing started at 7:15 a.m. loacal time [url=http://www.cheapjerseystexans.com/lamar-miller-jersey/]Lamar Miller Jersey[/url] , resulting in the killing of two civilians - Ghizar Ahmed and Fazal Hussain.

Five civilians, including three women, were injured in the firing, a Foreign Ministry statement said.

Director General on the South Asian Desk at the Foreign Ministry Mohammad Faisal summoned the Indian Deputy High Commissioner and lodged a formal protest.

"The deliberate targeting of civilians is indeed condemnable and contrary to human dignity and international human rights and humanitarian laws," the Pakistani official told the Indian envoy.

Pakistan and India had declared ceasefire along the LoC in 2003. Both routinely accuse each other of ceasefire violation.

"The Director General urged the Indian side to respect the 2003 Ceasefire Understanding; investigate this and other incidents of ceasefire violations; instruct the Indian forces to respect the ceasefire [url=http://www.cheapjerseystexans.com/deandre-hopkins-jersey/]DeAndre Hopkins Jersey[/url] , in letter and spirit and maintain peace on the LoC," the Foreign Ministry said.

Chinese Premier Li holds talks with German Chancellor Merkel in Berlin

China's submersible Jiaolong conducts 5th dive in Mariana Trench

Youngsters celebrate Int'l Children's Day in various ways across China

Hong Kong's 20th return anniversary to be celebrated on July 1

Cheongsam show held at Sanshuiwan scenic spot in Taizhou City

In pics: Amboseli National Park in Kenya

In pics: outdoor cultural performance given by Ulanmuqi in N China

Water park attracts many citizens in SW China's Chongqing

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